Inhibiting NDMA-generated Spice Essential Oil Compound Inhibitors in Simulated Nitrosation System in Vitro

In order to effectively inhibit the formation of N-nitrosodimethylamine(NDMA),single factor experiments were used to study nine kinds of common spice essential oil in a simulated nitrosation reaction system. Andquadratic regression orthogonal combination design were used to screen the optimal ratio. Results showed that all nine spice essential oils inhibited the formation of NDMA. The optimal ratio of quadratic regression orthogonal combination design were pepper 2.078 mL/L,ginger 3.118 mL/L,Chinese prickly ash 3.692 mL/L,star anise 2.833 mL/L and clove 0.218 mL/L,and the inhibition rate of NDMA was 64.412%±0.25%.