Study on the antioxidation of the flavonoids from fructus sophorae in vitro

Extraction of total flavonoids from fructus sophorae was investigated using reflux method.The antioxidation activity of the extract was evaluated in vitro by using methods of DPPH., pyrogallol autoxidation and phenanthroline with V C as reference substance.The results showed that compared with the positive control V C, the flavonoids from fructus sophorae had stronger capacity of scavenging on O 2., .OH, with IC 50 0.0127 mg/mL and 0.0160mg/mL respectively, but weaker capacity of scavenging on DPPH., with IC 50 0.0192mg/mL.It was indicated that the flavonoids from fructus sophorae had certain antioxidant capacity.