Abstract: The OBE (Outcome Based Education) teaching concept has become a global consensus and one of the core principles of engineering education certification. Applied undergraduate colleges are positioned to serve local industries and cultivate applied talents that meet the needs of local industries. Case teaching is an effective method for students to actively participate in the classroom and improve the teaching effect. At present, in the field of food science and engineering, most of the case teachings are related to some specific events such as food safety that have occurred, while there is almost no case related to productive practice. The authors developed and implemented practical cases of food engineering production under the guidance of the OBE concept. To improve the practical effectiveness of case teaching, on the premise of consolidating students' basic knowledge, they are continuously guided to conduct comprehensive experiments, production practice, and graduation thesis in a specific field to create a characteristic training system of "basic knowledge-case teaching-comprehensive experiment-production practice-graduation thesis", so as to improve the comprehensive professional quality of students and cultivate high-level application-oriented talents.