Abstract: To explore the profiles of phytochemical components in geographical indication product of China Lilium davidii var. unicolor, the bulbs of which derived from five major producing areas of Gansu Province (Yuzhong County, Lanzhou City, Qilihe District, Lanzhou City, Lintao County, Dingxi City, Weiyuan County, Dingxi City, Yongjing County, Linxia City) were detected using ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC-QTOF MS). Based on untargeted metabolomics technology, a total of 62 phytochemical components were putatively annotated in the bulbs of L. davidii var. unicolor. Among them, there were 22 kinds of amino acids, peptides and their derivatives (e.g., glutathione), 9 kinds of lipids and phospholipids (e.g., lyso-phosphatidylcholin), 7 kinds of saccharides (e.g., rhamnose), 7 kinds of phenolic acids (e.g., ferulic acid and caffeic acid), 4 kinds of flavonoids (e.g., kaempferol), 4 kinds of natural vitamins (e.g., riboflavin and vitamin C), 3 kinds of phenolamines (e.g., feruloyl putrescine), 2 kinds of coumarins (e.g., gerberinside), 2 kinds of alkaloids (e.g., trigonelline), terpenoids (e.g., abietic acid) and triterpenoid saponins (e.g., eleutheroside E). The study would provide richer data and scientific evidence for the investigation and utilization of L. davidii var. unicolor.