Abstract: In order to timely understand the research status and hot spots as well as the development trends of photodynamic sterilization worldwide, this paper adoptes bibliometrics method to analyze the research literatures in the filed of photodynamic sterilization which is collected through the core database of Web of Science from 2002 to 2022, aiming to provide references for researchers in related research fields. Meanwhile, the visualization analysis of different countries and regions, institutions and authors are carried out by the Citespace software, the cluster analysis and emergence analysis of the keywords in the field of photodynamic sterilization research are performed. According to the analysis, the selection and transformation of photosensitizers, the selection and optimization of light sources, and the extension of food shelf life are the research fields of photodynamic sterilization technology in the field of food. In addition, photodynamic combines with other cold sterilization technologies to enhance sterilization effect will also be a promising research field in the coming future.