Abstract: In order to evaluate the harm of pesticide residues and explore the high-risk hazard factors and risk levels in different varieties of Xinjiang red jujube (winter jujube, Hui jujube and Jun jujube), 93 pesticides were determined by liquid chromatography-mass spectrometry and gas chromatography-mass spectrometry. The differences of pesticide residues in different varieties of jujube were compared, and the risk of pesticide residues in jujube samples were evaluated and ranked. A total of 16 kinds of pesticides were detected in 85 red jujube samples. The detection rates and types of pesticide residues in different varieties of red jujube were different. The detection rates of pesticide residues in winter jujube were 93.33% and 15 kinds of pesticides were detected, which were significantly higher than those in Hui jujube and Jun jujube. The risk of chronic dietary intake and acute dietary intake of pesticides detected in jujube were far less than 100%, which was in an acceptable range. The high and medium risk pesticides in winter jujube were methamamectin benzoate, mite, biphenthrin, thiophosphate, acetamidine and permethrin. The medium risk pesticides in Hui jujube and Jun jujube were: phosphorus, propylene bromphosphorus and acetamidine. There were high risk and medium risk samples in the winter jujube samples, but the Hui jujube and Jun jujube samples were both medium risk and low risk samples. The quality and safety of jujube in Xinjiang is generally good, but the risk of pesticide residue in winter jujube is generally high, which should be paid attention to.