Abstract: As a filling component of packaging materials, nano-cellulose can improve the mechanical properties and barrier properties of the materials, and can improve the thermal properties and degradation properties of composite materials. This article briefly introduces cellulose and nano-cellulose, focusing on the preparation methods of nano-cellulose (chemical method, biological method and physical mechanical method, etc.) and its application in food packaging materials (preservative and antibacterial packaging materials, active packaging materials and high barrier packaging materials, etc.). Finally, the research and development direction of nano-cellulose in the field of food packaging materials is prospected, with a view to provide theoretical support for the development of food packaging materials.