Abstract: In order to explore the difference of main functional components in leaves of different varieties of loquat, theoretical reference was provided for the grafting utilization of loquat leaves. The leaves of 14 loquat cultivars growing in Ankang, southern Shaanxi Province were used as materials to evaluate the quality of loquat leaves by measuring the contents of total flavonoids, total phenols, triterpenoid acids, polysaccharides, vitamin C, ABTS cations free radical scavenging rate and FRAP value.The results showed that, the leaves of‘Jialing’, ‘Peiyou’ and ‘Maihouhuang’ had higher contents of total flavonoids, total phenols and triterpenoid acids, stronger antioxidant activity, and better medicinal value and function. The content of polysaccharide and vitamin C in the leaves of ‘Xinong Loquat 2’ and ‘Jinyun’ were higher, which had better nutritional value. The results of principal component analysis showed that the top three varieties were‘Jialing’, ‘Maihouhuang’ and ‘Peiyou’.