Abstract: Because the probiotics raw materials are relatively systematic and have clear health effects in regulating intestinal flora and enhancing immunity, their health effects are more and more widely used in health food, and some strains have been expressly written by the State Administration for Market Supervision and Administration. Regulations allow the development of food for infants and young children. With the rapid development of science and technology and the continuous deepening of related research, other health functions of probiotic raw materials are constantly being explored, and the mechanism of action is constantly clarified, which provides more science for its development and application in the health food industry. This article describes the functional research progress, compliance basis, application status, development suggestions, precautions and prospects of probiotic raw materials in health foods in China, in order to provide references for the development and application of health foods of probiotic raw materials.