Abstract: Glycemic response(GR)refers to the effect of food on blood glucose fluctuation,which can reflect the digestion and metabolism of carbohydrate in the body. The determination of GR is very important for the diet guidance for diabetic patients,and the development of low glycemic index products. At present,the most authoritative method to test GR is human body test. In addition,animal test and in vitro evaluation methods have also become research focuses due to their advantages of low cost,easy operation and high throughput. This paper mainly reviews the research status of different methods on GR test including human test,animal test and in vitro digestion model,in order to provide guidance and help for the follow-up research.