Abstract: In this experiment,ultrasound-assisted extraction was used to extract carotenoids from Fuju peel. On the basis of single factor experiments,the extraction process was optimized by response surface analysis with liquid-solid ratio,extraction temperature,and ultrasonic power as influencing factors and extraction amount of carotenoids as response value. The results showed that the best carotenoid extraction effect was achieved under the conditions of liquid-to-material ratio,ultrasonic power and temperature was 59:1 (mL/g),240 W and 50 ℃,and the number of extractions was twice,the extraction time was 10 minutes.Under these conditions,the total carotenoids extracted from Fuju peel was(0.747±0.027) mg/g,which was basically consistent with the predicted value. This study not only optimizes the extraction process of carotenoids from Fuju peel,but also provides guidance for comprehensive utilization of Fuju.