Abstract: To optimize pretreatment conditions in comparing the purification effects of different types of solid phase extraction columns,a gas chromatography-mass spectrometry(GC/MS)method was established for the determination of 58 pesticide residues in chives.The samples were extracted by acetonitrile,cleaned-up with Cleanert PC/NH₂ solid-phase extractant,and determined by GC/MS using matrix-matched external standard method. The determination coefficients(R²)of all the 58 pesticides in the range of 65.2~1043.0 ng/mL were not less than 0.990. The limits of detection(LODs)were 0.001~0.007 mg/kg when signal/noise was 3(S/N=3). The limits of quantification(LOQs)were 0.003~0.024 mg/kg(S/N=10).For recovery test,there were three levels(low,medium and high)spiked in chives. The average recoveries of the method were 62.2%~125.2% and the relative standard deviations(RSDs,n=3)were 0.5%~9.5%. Compared with QuEChERS method,the method has the advantages of simple and rapid processing,high purification sensitivity and selectivity which is suitable for screening and quantitative analysis of multi-component pesticides in the chives matrix.