Abstract: Postharvest diseases of fruits and vegetables cause huge economic losses. Mycotoxins caused by some pathogens are harmful for the health of human and animals. Making use of chemical method may easily pollute the environment and remain toxicity to some extent.The use of chemical control is facing more and more restrictions. Biological control of postharvest decay of fruits,vegetables and grains using antagonistic yeasts has been explored widely as one of several promising alternatives tochemical fungicides. In this paper,the stype,effect,mechanism of antagonisticyeast and how to improve the biocontrol efficiency were reviewed.