Abstract: In order to compare the differences of adult yaks meat nutritional content in different regions, the nearly 7 years old male yaks in Jiulong county of Sichuan province, Diqing state of Yunnan province and Bazhou of Xinjiang province were selected as the research object. The contents of crude protein, crude fat, ash, dry matter, cholesterol, amino acid and fatty acid were measured and analyzed in a systematic manner on the back of its longest muscle sample.Their differences were compared by using principal component analysis(PCA). To provide theoretical basis for the development and utilization of yaks meat resources in various regions. The results showed that three regions of conventional nutrients the crude protein, ash and dry matter in the yaks meat were no obvious difference(p>0.05).the crude fat, cholesterol, amino acid and fatty acid differed significantly among yaks meat samples from different regions(p<0.05 or p<0.01). The content of crude fat and cholesterol of yaks meat in Bazhou of Xinjiang province were the highest, the content of crude fat of yaks meat in Diqing state of Yunnan province was the lowest, the content of cholesterol of yaks meat in Jiulong county of Sichuan province was the lowest.The content of proline in Jiulong county of Sichuan province yaks meat was significantly higher than that of Bazhou(p<0.01), and other amino acid components in three areas yaks meat had no significant difference(p>0.05).The contents of the fatty acids in three regions were significantly different.There are significant differences in the quality of yaks meat in three regions.But all three regions of yaks meat have the characteristics of "high protein, low fat, rich nutrition", the amino acid content of yaks meat in Jiulong county of Sichuan province is the most abundant, the unsaturated fatty acids of yaks meat in Bazhou of Xinjiang province is the most abundant.