Abstract: Cyclic adenosine monophosphate ( c AMP) is an important physiologically active substance in the body, which can regulate the various functional activities of the cells and has a bright future in development and utilization prospects.This paper reviews the progress in extraction, separation and purification, detection method and the application value of clinical, functional food of c AMP in recent years, discuses the development trend and application prospect of c AMP, and provides a reference for the further development of jujube resources and research of c AMP.