从荒漠肉苁蓉分离苯乙醇苷产生的废弃液中结晶甘露醇
Crystallizing mannitol from discarded liquid produced in the process of separating phenylethanoid glycosides from Cistanche deserticola
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摘要: 荒漠肉苁蓉中分离苯乙醇苷的工艺中,大量甘露醇因难以与其它糖类分离而被一起丢弃。为了从这些废弃的糖溶液中分离纯化甘露醇,本文开发了一套甘露醇的结晶工艺。分别对影响结晶过程的3个主要因素（包括糖溶液的密度、结晶时间和结晶温度）进行了单因素实验。结果表明,适宜的操作参数为:糖溶液的密度为1.211.27 g/m L,结晶时间为2430 d,结晶温度为-100℃。在单因素实验的基础上,采用响应曲面法对结晶的工艺参数进行优化。结果表明最优操作条件为:糖溶液的密度为1.24 g/m L,结晶时间为28 d,结晶温度为0℃。在此条件下,甘露醇的回收率和纯度分别可达70.04%和87.17%。以上结果表明,荒漠肉苁蓉中分离苯乙醇苷的工艺中,废弃的糖液可以用于回收甘露醇。本研究获得的模型可以用来优化甘露醇结晶过程。Abstract: In the process of producing phenyethanoid glycosides from Cistanche deserticola,large quantity of mannitol was discarded along with the carbohydrate solution.To obtain mannitol from these discard solution,a crystallizing process was carried out.The effects of three main influencing factors( including density of carbohydrate solution,crystallizing time and temperature)on both recovery rate and purity of mannitol were tested. Results of single- factor experiment showed that three appropriate operational parameters were: 1.21~1.27 g/mL,24~30 days and-10 ~0 ℃. Response surface methodology was used to optimize crystallizing process.Results illustrated that the optimal operational conditions were as follows: density of carbohydrate solution was 1.24 g/mL,crystallizing time and temperature were 28 days and 0 ℃.Under these conditions,the recovery rate and purity of mannitol were 70.04% and 87.17%. Therefore,discarded carbohydrate solution produced in the process of separating phenyethanoid glycosides from Cistanche deserticola can be used to separate mannitol.Besides,the models obtained in this study can be used to optimize the crystallizing process of mannitol.
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