Abstract: Calcium is an essential element of the human body,and plays a significant role in health. However,the dietary intake of calcium in China is only half of the recommended intakes. Considering the low bioavailability of traditional calcium supplements,developing the safe and efficient calcium supplements is imperative. Calcium-binding peptides from foodstuffs are safer and more reliable,which have caused the extensive concern of researchers.In this review,several typical calcium- binding peptides from foodstuffs,and methods of purification,identification and structural analysis had been summarized,which would provide reference for the application of calcium- binding peptides in functional food.