Abstract: In recent years,the food poisoning and deaths caused by food- borne pathogens have frequently occurred in the world,serious harm to human health,food- borne microorganisms have become the No.1 killer of human health.At present,the research on the technology of food- borne pathogenic bacteria detection has become a hot spot for international scholars,and the focus of the research is on rapid detection technology.However,in the rapid detection,especially molecular biology techniques,pre- enrichment process is required,how to shorten the pre- enrichment time and improve the enrichment effect is a problem to solve that in the development of rapid detection. In this paper,outbreaks of Salmonella,Staphylococcus aureus,Listeria monocytogenes,Vibrio parahaemolyticus and Shigella are discussed and focused on the status of the pre- enrichment of first four bacteria,in order to acquaintance the existing of pre- enrichment of rapid detection and achieve a shorter time to detect foodborne pathogens.