Abstract: Lactic acid bacteria are a class of probiotics widely used in food,medical and cosmetics industry.As an essential trace element for human,selenium( Se) plays a critical role in metabolism and immunoregulation.In recent decades,Se-enriched lactic acid bacteria attract extensive attention due to their outstanding antioxidant,anti-inflammatory,antitumor activities and the ability to transform inorganic selenium into organic form,which is beneficial to human absorption. However,further studies about metabolic pathways of Se by LAB are needed;meanwhile,it is necessary to test and evaluate the toxicities and side effects of Se-enriched probiotics and their fermented foods.In this paper,the oxidation state of selenium,the effects on the growth of LAB by selenium,the transformation of organic selenium by LAB,bioactivities of Se-enriched LAB and Se-enriched functional foods were summarized.