液体发酵的桑黄多糖对小鼠免疫功能的影响

Effect of polysaccharides from Phellinus igniarius by liquid fermentation technology on mouse's immunity function

摘要: 研究液体发酵分离纯化得到的桑黄多糖对小鼠免疫功能的影响。研究桑黄多糖对小鼠的免疫器官、碳廓清率以及IL-1、IL-2、IL-4、IL-6、IFN-γ、TNF-α细胞因子的影响,发现桑黄多糖能显著提高小鼠胸腺重量和脾脏重量,增强小鼠碳廓清率,增加IL-2和IFN一γ的含量,降低IL-1、IL-6、TNF-α的含量。证实桑黄多糖能显著增强小鼠的机体免疫力,有一定的抗炎作用。

Abstract: To study the effect of polysaccharides from Phellinus igniarius by liquid fermetation technology on mouse's immunity function.It mainly studied the immune organs in mice,carbon clearance rate,and IL-1,IL-2,IL-4,IL-6,IFN-γ,TNF-α affected by P. igniarius polysaccharide. The results showed that it could significantly increase the weight of thymus and spleen,enhance carbon clearance rate,increase the content of IL-2 and IFN-γ,reduce the content of IL-1,IL-6 and TNF-α. It was confirmed that polysaccharides from Phellinus igniarius could significantly enhance immunity,and there was a certain anti-inflammatory effects.