Abstract: The effects of radiation dose,zearalenone initial concentration,moisture content on the degradation rate and degradation rate constant of zearalenone( ZEA) in corn flour by γ- ray irradiation,the stability of corn nutrients at different radiation doses and establishment of ZEA residual method in maize flour were studied in this paper.The results indicated that the ZEA degradation rate was increased with elevated radiation dose. When corn flour was360~1950 μg / kg and zearalenone degradation rate was 33.85% ~ 43.28% at 50 k Gy,γ- ray degradation of ZEA obeyed the first order kinetics,the degradation rate of ZEA was not significantly affected by the initial concentration of the toxin( p > 0.05),but the degradation rate of the low initial concentration ZEA in maize flour was higher than that of high concentration.The degradation of ZEA were not significantly affected by the content of 9.41% ~12.35%in the corn flour( p > 0.05). 50 k Gy radiation dose had no significant effect on the corn flour protein,fat,starch content,but the lysine content was decreased by 8.11%. In conclusion,γ- ray had a degradation effect on ZEA,which can be used to predict the degradation rate of the first order reaction kinetics equation.