Abstract: Maca was a rare medicinal and edible plant,originating in Peru. It contains abundant nutrients.Maca has the ability to relieve fatigue,improve sleep,improve the function and antioxidant and other biological activity.Macamides were the special active substances in Maca,having strong biological activity. The content of the macamides in maca was low. At present,the method of solvent reflux,ultrasonic extraction,HPLC and liquid chromatography- mass spectrometry were used to detect it. In this paper, the extraction and analysis of macamides were reviewed,which provides a reference for its further research.