Abstract: Egg allergy is a kind of food allergy,which can also be called allergic reaction where the body reacts with egg protein.The material basis of food allergy is epitope antigen and antibody counterpoint,and the key to solve the problem of food allergy is to study the allergens epitope deeply.In this paper,the six main egg allergens and the epitope mapping method were introduced. Meanwhile epitopes of OVA,OVM,OVT and LYS were reviewed in details.This review can provide theoretical guidance for the further egg allergy research,and also be used for the quantitative detection of the epitope and provide some reference for developing safe egg allergens vaccine.