Abstract: Box- Behnken Design was employed to analyze and optimize the effect of Chinese herbal medicine extracts, PVA and monoglyceride on the fresh- keeping efficiency of eggs with water loss rate and the total bacteria colonial as responses. The results showed that optimal ratio were Chinese herbal medicine extracts0.45 g / m L, PVA 10.68 g / m L and monoglyceride 2.05 g / m L.Under the conditions, the water loss rate, total bacterial colonial and HU of coated eggs was 5.84%, 4.54 lgcfu / g and 55.1 respectively after 30 days storage at 25 ℃, RH60%, which was significantly better than the control group.