Abstract: The effect of different levels of Citric acid- modified resistent starch( CARS) and Low- molecular- weight Oxidized Konjac glucomannan( LM- OKGM) on growth,blood lipid,the composition of liver and muscle of Schizothorax prenanti Tchang( SPT) were measured.The results showed that the two kinds of polysaccharides in a high does promoted the growth of SPT better than the low dose and LM- OKGM was better than CARS.H- LM- OKGM significantly promoted the growth,weight gain rate was 20.76% and specific growth rate was0.31% / d( p < 0.05). In addition,the two kinds of polysaccharides in a high does reduced TC and TG in serum of SPT significantly( p < 0.05).The content of HDL- C could be increased from 1.97 mmol / L to 3.21 mmol / L in serum of SPT eated H- LM- OKGM group( p < 0.05),while feeding the H- CARS only reached to 2.42 mmol / L( p > 0.05).However,the reduction of the fat content in the liver tissue on CARS was more significant than LM- OKGM( p < 0.05). Meanwhile,CARS didn't produce a significant effect on the crude fat of back muscle( p > 0.05).But H- LM- OKGM increased the crude fat content in back muscle to 2.69%( p < 0.05),and LM- OKGM increased to2.01%( p > 0.05).In summary,the two kinds of polysaccharides were able to promote the growth,lower blood lipids and increase the content of HDL- C of SPT in different degrees. LM- OKGM could increase back muscle fat deposits and promote the blood lipid better compared to CARS.SPT growth and lower blood lipids. CARS could prevent SPT suffering from fatty liver more effectively than LM- OKGM.