Abstract: To optimize the extraction process conditions for total flavonoids from the Chaenomeles Speciosa pomace of Chongqing.On the basis of the single- factor test,effects of solid- liquid atio,ethanol concentration,extraction time,extraction temperature and extraction times on the extraction rate were studied by taking the content of total flavonoids as the index.The influence degree of four factors on the extraction rate of total flavonoids was in the order of extraction temperature > ethanol concentration > extraction time > solid- liquid ratio. Among them,temperature had relatively significant impacts on the yield rate of total flavonoids from Chaenomeles Speciosa pomace. The best extraction technology: concentration of 50% ethanol as xtraction solvent,60℃extraction temperature,1∶30( g·m L- 1) solid-liquid ratio,80 min extracting time.Under this condition,the yield was 0.527%.This method was simple convenient and accurate for the detection of total flavonoids.