超声辅助提取禹州漏芦中α-三联噻吩工艺研究

池承灯; 施清凉; 陈紫红; 陈继承

doi:10.13386/j.issn1002-0306.2014.22.051

超声辅助提取禹州漏芦中α-三联噻吩工艺研究

Optimization of ultrasonic-assisted extraction of α-terthienyl

摘要

摘要: 目的:利用响应面分析法优化超声辅助提取禹州漏芦中α-三联噻吩工艺。方法:以α-三联噻吩提取率为考察指标,选择超声功率、时间和提取温度为随机因子,进行3因素3水平的Box-Behnken中心组合设计,分析3个因素对响应值的影响。结果:超声辅助提取禹州漏芦中α-三联噻吩的最佳提取功率350W;超声时间42min;超声处理温度41℃。该条件下α-三联噻吩的预测值86.5%,验证值85.1%,理论的相对误差为1.6%。结论:该优化条件可行,为提高禹州漏芦中α-三联噻提取率提供理论依据。

Abstract: Objective:To optimize the ultrasonic-assisted extraction conditions of α-terthienyl in Radix Echinopsis by the response surface analysis methodology. Methods:The yield of α-terthienyl was selected as investigation index, choosing the power of ultrasonic, extraction temperature and extraction time as random factors, and three-factors-three-levels Box-Behnken central composition designed to investigate the effect on the yield ofα-terthienyl. Results:The optimal conditions were ultrasonic power of 350 W, extraction time of 42 min and extraction temperature of 41℃. Under these conditions, the predicted value of 86.5% was inosculated with the actual value of 85.1%. The relative error was only 1.6%. Conclusion:These methods were feasible for optimizing extraction processing and would efficiently improve the extractions of α-terthienyl in Radix Echinopsis.