Abstract: The dynamic models for alpha-pinene fermentation by Escherichia coli were studied. The kinetic models for cell growth, alpha-pinene production and substrate consumption were proposed with Logistic equation, Luedeking- Piret equation and Luedeking- Piret- Like equation though the optimal parameters estimation and nonlinear least-squares fitting method. The observed and estimated values of the models were in a good agreement, the result showed that the models could provide a reasonable description for the fermentation process of alpha-pinene.