Abstract: Five different polarity extracts from Mosla chinensis ‘Jiangxiangru' were prepared by solvent extraction method. To compare the bacteriostatic activity of different extracts on Staphylococcus.aureus, Escherichia.coli and Bacillus subtilis, disk diffusion method and broth dilution method were used. The results showed that four organic solvent extracts had various bacteriostatic activities on the tested germ, but the aqueous extract had little bacteriostatic activity. In addition, the ethyl acetate extract had the lowest MIC (minimal inhibitory concentration) , which was 15.60μg/mL. While, MIC of petroleum ether extract and ethanol extract were31.25μg/mL. Thus, Mosla chinensis ‘Jiangxiangru' had antibacterial activity, and the ethyl acetate extract had the most significant effect.