鞘氨醇胶Ss的降解及抗氧化活性的研究

Study on degradation and antioxidant activities of sphingan Ss

摘要: 对鞘氨醇胶Ss进行氧化降解,得到重均分子量为10.3ku的降解产物,利用红外光谱和核磁氢谱对降解产物进行结构表征,并对其抗氧化性进行测试。结果表明,降解处理后鞘氨醇胶Ss的抗氧化性显著提高,氧化降解24h的样品还原力最高,降解产物清除羟自由基的IC50为8.32mg/mL,清除超氧阴离子的IC50为12.13mg/mL。

Abstract: Sphingan Ss was degraded by oxidative method, and a degradation product with weight-average molecular weight 10.3ku was obtained. The structure of degraded sphingan Ss was characterized by infrared spectrum and1H-NMR. The antioxidant capacity was investigated. The results showed that degradation product exhibited higher antioxidant activity than the sphingan Ss. The value of reducing power reached the maximum after a degradation time of 24 hours. The IC50 of scavenging hydroxyl free radical and superoxide anion was 8.32mg/mL and 12.13mg/mL, respectively.