Abstract: It is generally believed that a major cause of dairy products quality problem is the light punishment of dairy products enterprise's bad behavior. But the other influencing factors effecting on the quality safety level of dairy products, especially for quantitative research of factors remains to go deep. In order to distinguish the influence degree of various factors on dairy safety of quality, the multi-factor sensitivity analysis method which is the orthogonal analysis method was used to analysis the influence factors to improve the safety of quality of dairy products this paper. According to the sensitivity analysis of various influence factors of the safety of quality of dairy products, unit regulatory costs, defect milk dairy products as security to obtain extra profits and unit prevention costs of producer are the main factors affecting the quality of dairy products.