Abstract: The market survey about content of Pb2+ and Cd2+ in nine common edible mushrooms in Dalian was carried out, and the correlation of Pb2+ and Cd2+ content in the medium and the accumulation of mushroom mycelium was analyzed.Results showed that the moisture content of the fresh edible mushrooms Pleurotus eryngii, Hypsizygus marmoreus, Pholiota nameko in Dalian market were above 91.0%.Pb2+ detection rate of the commercial fresh edible mushrooms was 100%, the average content was 0.2819mg/kg, but less than 1.0mg/kg, Cd2+ was not detected in the edible mushrooms.Liquid culture of the edible mushroom mycelium, low concentrations of Pb2+ and Cd2+ in the medium could promote the growth of edible fungi, high concentrations of Pb2+ and Cd2+ produce inhibition on edible fungi growth, and with the Pb2+ and Cd2+ content increased, the accumulation rate became smaller.