响应面分析优化菊粉的十二烯基琥珀酸酐改性工艺研究

Study on dodecenly succinic anhydride-modified inulin

摘要: 为了研究菊糖的十二烯基琥珀酸酐改性工艺条件,以菊糖、硼氢化钠及十二烯基琥珀酸酐用量、反应时间、反应pH以及反应温度为影响因素,以十二烯基琥珀酸酐的取代度为考察指标,运用Plackett-Burman设计筛选出3个对菊糖的十二烯基琥珀酸酐取代度影响显著因素,即十二烯基琥珀酸酐用量、反应pH和反应时间。用响应面分析实验优化十二烯基琥珀酸菊糖酯改性工艺。十二烯基琥珀酸菊糖酯改性最优工艺:菊糖4g,硼氢化钠0.015g,十二烯基琥珀酸酐0.94g,反应时间为6.8h,反应pH8.5,反应温度35℃,菊糖的十二烯基琥珀酸酐取代度为0.0140±3.33E-05。

Abstract: In order to study optimum conditions for dodecenly succinic anhydride-modified inulin,effects of the amount of inulin,the dosage of sodium borohydride and dodecenly succinic anhydride (DDSA),pH,time and temperature used on the degree of substitution of dodecenly succinic anhydride - modified inulin were investigated. Plackett -Burman was adopted to screen out the important factors,which were the dosage of dodecenly succinic anhydride,pH and time used. The optimum reaction conditions were obtained by response surface analysis:inulin 4g,sodium borohydride 0.015g,dodecenly succinic anhydride 0.94g,time 6.8h,pH8.5, temperature 35℃ ,and the degree of substitution of dodecenly succinic anhydride-modified inulin is 0.0140 ± 3.33E-05.