七叶莲果实的抗炎镇痛作用研究

Anti-inflammatory and anti-nociceptive effect of the fruit of Schefflera arboricola Hayata in experimental animal models

摘要: 目的:研究七叶莲果实水提物的抗炎镇痛作用。方法:采用热板法疼痛模型、醋酸诱发的小鼠扭体疼痛模型评价水提物的镇痛作用和二甲苯致小鼠耳廓肿胀模型评价水提物的抗炎作用。结果:七叶莲果实水提物对热板、醋酸导致的疼痛,二甲苯所致的耳廓肿胀均有不同程度的抑制作用。结论:七叶莲果实水提物有较强的抗炎镇痛作用。

Abstract: Objective:To determine the anti-nociceptive and anti-inflammatory of the fruit of Schefflera arboricola Hayata. Methods:The pain-killing effect was tested by hot plate model and body twisting model induced by acetic acid in mice. The anti-inflammatory functions were observed and compared by the method of xylene-induced ear edema in mice. Results:The fruit of Schefflera arboricola Hayata had analgesic effect on the pain caused by hot and acetic acid, and could inhibit the inflammation induced by xylene and significantly reduce ear swelling of mice. Conclusion:These results suggested that the fruit of Schefflera arboricola Hayata had anti-nociceptive and anti-inflammatory effect.