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中国精品科技期刊2020
蛋氨酸羟基类似物对肉鸡肠道氧化还原状态的影响[J]. 华体会体育, 2012, (21): 99-103. DOI: 10.13386/j.issn1002-0306.2012.21.025
引用本文: 蛋氨酸羟基类似物对肉鸡肠道氧化还原状态的影响[J]. 华体会体育, 2012, (21): 99-103. DOI: 10.13386/j.issn1002-0306.2012.21.025
Effect of 2-hydroxy-4- (methylthio) butanoic acid on intestinal redox state of broiler chickens[J]. Science and Technology of Food Industry, 2012, (21): 99-103. DOI: 10.13386/j.issn1002-0306.2012.21.025
Citation: Effect of 2-hydroxy-4- (methylthio) butanoic acid on intestinal redox state of broiler chickens[J]. Science and Technology of Food Industry, 2012, (21): 99-103. DOI: 10.13386/j.issn1002-0306.2012.21.025

蛋氨酸羟基类似物对肉鸡肠道氧化还原状态的影响

Effect of 2-hydroxy-4- (methylthio) butanoic acid on intestinal redox state of broiler chickens

  • 摘要: 目的:研究蛋氨酸(DLM)、蛋氨酸羟基类似物(HMTBA)及其钙盐(HMTBA-Ca)对肉鸡肠道氧化还原状态的影响。方法:1日龄罗斯肉鸡(44g)随机分为对照组(基础日粮)和实验组(在基础日粮中分别添加0.1%和0.2%的DLM、HMTBA及HMTBA-Ca),共7个处理组。结果:与对照组相比,0.1%HMTBA组和0.1%HMTBA-Ca组可显著降低全血ROS水平,提高肠道GSH/GSSG和T-AOC,降低血浆及组织MDA含量。0.2%HMTBA组和0.2%HMTBA-Ca组可显著提高血浆和组织CAT活性。基础日粮中添加HMTBA和HMTBA-Ca均可使肠绒毛高度升高、隐窝深度下降、V/C升高。此外,0.1%HMTBA组和0.1%HMTBA-Ca组ROS水平及MDA含量均低于0.1%DLM组,肠绒毛高度和V/C则高于0.1%DLM组。结论:与DLM相比,HMTBA及HMTBA-Ca能更好地提高肠道抗氧化能力,降低ROS水平,维持肠道氧化还原稳态,促进肠道健康发育。 

     

    Abstract: Objective:To research the effects of methionine sources methionine (DLM) , 2-hydroxy-4- (methylthio) butanoic acid (HMTBA) and 2-hydroxy-4- (methylthio) butyrate calcium (HMTBA-Ca) on intestinal redox state of broiler chickens. Method:One hundred and five (105) broiler chickens (44g) were randomly divided into 7 groups (15 birds per group) , and each group was assigned to 1 of 3 treatments. Birds in each group were kept in three coops (5 broilers per coop) . All broilers were offered the same basal diet with added DLM, HMTBA and HMTBA -Ca at levels of 0 (control group) , 0.1% and 0.2%. Results:Compared with control group, basal diet with 0.1% HMTBA group and 0.1% HMTBA-Ca group could decrease the level of free radicals in whole blood significantly, enhance the activity of GSH/GSSG, T-AOC of the serum and tissues significantly, decrease the level of MDA significantly. Compared with control group, basal diet with 0.2% HMTBA group and 0.2% HMTBA-Ca group could enhance the activity of CAT of the serum and tissues significantly. Basal diet with added HMTBA, HMTBA-Ca could enhance the intestinal villus height (V) and the ratio of the villus height to recess depth of broilers (V/C) , decrease the intestinal recess depth (C) of broilers significantly. Compared with 0.1% DLM group, ROS, MDA levels were lower and V, V/C were higher in basal diet with 0.1% HMTBA group and 0.1% HMTBA-Ca group. Conclusion:Compared with DLM, HMTBA and HMTBA-Ca could better increase the intestinal antioxidative capacity, decrease the level of free radicals, steady intestinal redox state, promote the intestinal development healthily.

     

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