蚕蛹油不饱和脂肪酸微胶囊的制备及其性质研究
Study on preparation of silkworm pupa silkworm pupa unsaturated fatty acids microcapsules and its properties
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摘要: 以壳聚糖、乳糖等为壁材,蚕蛹油不饱和脂肪酸为芯材,通过喷雾干燥法制备微胶囊。以微胶囊包埋率为评价指标,采用旋转曲面法设计正交实验,优化微胶囊壁材配比为:脱油大豆卵磷脂添加量为壳聚糖的13%(w/w),复配壁材乳糖与基础壁材壳聚糖比例为1.42:1.0(w/w),芯材蚕蛹油不饱和脂肪酸与总壁材质量比0.52:1.0(w/w),此时微胶囊包埋率达到83.31%,效果达到最佳;蚕蛹油不饱和脂肪酸经微胶囊化后流动性良好,且壁材有效阻隔芯材过氧化,货架期可延长至8个月;模拟胃肠液实验中,被壁材包裹的不饱和脂肪酸在胃液中受到保护缓慢释放,在肠液中可迅速释放。Abstract: Encapsulation of silkworm pupa unsaturated fatty acids with chitosan and lactose as the main wall material was carried out by a spray-drying process.Response Surface Methodology (RSM) was used to study and optimize technological parameters of the ratio of lecithin, ratio of lactose and chitosan and ratio of core and wall materials.The optimal condition was determined as follows:the ratio of lecithin to chitosan of 13% (w/w) , ratio of lactose to chitosan of 1.42:1.0 (w/w) and ratio of core to wall of 0.52:1.0 (w/w) , at which the microencapsulation efficiency (MEE) reached 83.31%.The encapsulated silkworm pupa unsaturated fatty acids produced by this method had good physicochemical properties and dispersibility.The shelf life was extended to 8 months and core material was protected well from oxidation.The release ability was studied.Microcapsules were subjected to an invitro gastrointestinal fluid, in which it showed rapid-release property in intestinal fluid model and sustained-release property in gastric juice.
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