Abstract: An inductively coupled plasma mass spectrometry (ICP-MS) with an octopole reaction/ollision cell and shield torch system was employed for the simultaneous determination of released heavy metal elements in food plastic bag.The elements of Cr, Mn, Ni, Cu, Zn, As, Cd, Sn, Sb and Pb were determined by introducing the hydrogen gas or helium gas into the reaction/collision cell to eliminate the interference of multi-element molecules and ions.Ge, In and Tb were used to correct the matrix interference and drift.Under the optimal conditions, the detection limits of the 10 elements were in the range of 0.003 ～ 0.153μg/L with the relative standard deviation (RSD) 0.70% ～ 2.51%, and the recovery of the samples was in the range of 90.0% ～ 106.0%.The method is easy, rapid and accuracy.